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1

Synthesis of Antisense Oligonucleotides Conjugated to a Multivalent Carbohydrate Cluster for Cellular Targeting

Maier, Martin A., Yannopoulos, Constantin G., Mohamed, Nazim, Roland, Arlene, Fritz, Hans, Mohan, V., Just, George, Manoharan, Muthiah

Journal:

Bioconjugate Chemistry

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

2

The Greek Tragedy; Greece Under Military Rule;

Legg, Keith R., Tsoucalas, Constantine, Clogg, Richard, Yannopoulos, George

Journal:

American Political Science Review

Year:

1973

Language:

english

File:

PDF, 301 KB

english, 1973

3

Design and Synthesis of a Potent Macrocyclic 1,6-Naphthyridine anti-Human Cytomegalovirus (HCMV) Inhibitors.

Guy Falardeau, Hugo Lachance, Annie St-Pierre, Constantin G. Yannopoulos, Marc Drouin, Jean Bedard, Laval Chan

Journal:

Year:

2005

File:

PDF, 19 KB

2005

4

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides

Laval Chan, Oswy Pereira, T.Jagadeeswar Reddy, Sanjoy K. Das, Carl Poisson, Marc Courchesne, Mélanie Proulx, Arshad Siddiqui, Constantin G. Yannopoulos, Nghe Nguyen-Ba, Caroline Roy, Daniel Nasturica,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

5

Design and synthesis of a potent macrocyclic 1,6-napthyridine anti-human cytomegalovirus (HCMV) inhibitors

Guy Falardeau, Hugo Lachance, Annie St-Pierre, Constantin G. Yannopoulos, Marc Drouin, Jean Bédard, Laval Chan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

6

Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase

T.Jagadeeswar Reddy, Laval Chan, Nathalie Turcotte, Melanie Proulx, Oswy Z. Pereira, Sanjoy K. Das, Arshad Siddiqui, Wuyi Wang, Carl Poisson, Constantin G. Yannopoulos, Darius Bilimoria, Lucille L'Heu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

7

Zur Kettenbruchtheorie im Dreidimensionalen

Constantin Yannopoulos

Journal:

Mathematische Zeitschrift

Year:

1942

Language:

german

File:

PDF, 261 KB

german, 1942

8

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

Laval Chan, Sanjoy K. Das, T.Jagadeeswar Reddy, Carl Poisson, Mélanie Proulx, Oswy Pereira, Marc Courchesne, Caroline Roy, Wuyi Wang, Arshad Siddiqui, Constantin G. Yannopoulos, Nghe Nguyen-Ba, Denis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

9

HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY

Constantin G. Yannopoulos, Ping Xu, Feng Ni, Laval Chan, Oswy Z. Pereira, T. Jagadeeswar Reddy, Sanjoy K. Das, Carl Poisson, Nghe Nguyen-Ba, Nathalie Turcotte, Melanie Proulx, Lilianne Halab, Wuyi Wan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 466 KB

english, 2004

10

Docking Ligands into Flexible and Solvated Macromolecules. 2. Development and Application of Fitted 1.5 to the Virtual Screening of Potential HCV Polymerase Inhibitors

Corbeil, Christopher R., Englebienne, Pablo, Yannopoulos, Constantin G., Chan, Laval, Das, Sanjoy K., Bilimoria, Darius, L’Heureux, Lucille, Moitessier, Nicolas

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 551 KB

english, 2008

11

Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition

Bichitra K. Biswal, Meitian Wang, Maia M. Cherney, Laval Chan, Constantin G. Yannopoulos, Darius Bilimoria, Jean Bedard, Michael N.G. James

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

12

331 Thiophene-2-carboxylic acids: a series of novel HCV polymerase inhibitors

Ming-Qiang Zhang, Laval Chan, Sanjoy K. Das, Thumkunta J. Reddy, Oswy Z. Pereira, Carl Poisson, Mélanie Proulx, Liliane Halab, Caroline Roy, Constantin G. Yannopoulos, Nghe Nguyen-Ba, Richard Bethell,

Journal:

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

13

Identification of N,N -Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase

Chan, Laval, Reddy, T. Jagadeeswar, Proulx, Mélanie, Das, Sanjoy K., Pereira, Oswy, Wang, Wuyi, Siddiqui, Arshad, Yannopoulos, Constantin G., Poisson, Carl, Turcotte, Nathalie, Drouin, Alexandre, Alao

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

14

2',3'-Cyclopropanated Nucleoside Dimers

Yannopoulos, Constantin, Zhou, Wen-Qiang, Nower, Peter, Peoc'h, Didier, Sanghvi, Yogesh, Just, George

Journal:

Year:

1997

File:

PDF, 275 KB

1997

15

The Differential Regulation by Glucagon and Growth Hormone of Insulin-Like Growth Factor (IGF)-I and IGF Binding Proteins in Cultured Rat Hepatocytes*

KACHRA, ZARIN, BARASH, ITAMAR, YANNOPOULOS, CONSTANTIN, KHAN, MASOOD N., GUYDA, HARVEY J., POSNER, BARRY I.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.25 MB

english, 1991

16

Structural basis for the RNA binding selectivity of oligonucleotide analogues containing alkylsulfide internucleoside linkages and 2′-substituted 3′-deoxyribonucleosides

Damha, Masad J., Meng, Bin, Wang, Daguang, Yannopoulos, Constantin G., Just, George

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 586 KB

english, 1995